Maintaining a breeding colony of mice is one method of generating and then ensuring an. Join the softmouse db community and discover the benefits of using a relational database management system to manage your mouse colony research. Micemanager online management software of laboratory mouse colony micemanager is a online interface to a database solution to manage your lab mice. Mouse colony management research animal resources and.
With pronuclear microinjection, a predesigned gene or genes are injected and randomly integrated into the mouse or rat genome. Jul 01, 2010 iseehear provides softmousedb mouse colony management database software for transgenic, knockout mice and breeding colony management. Dna detection in hair of transgenic mice a simple technique minimizing the distress on the animals. This software provide an easy way to work in realtime with your team members for free. The system can be seamlessly integrated with third party software for billing and compliance purposes, and the system can be expanded to have research labs also manage colony data. Softmouse internet colony management software softmouse tracks mice, rats, breeding, pedigrees, cages, litters, complex genotypes, mouselines, transgenic animals.
Breeding core, transgenic core, animal facility and labs our responsibilities are to help breeding cores, transgenic cores, animal facilities and labs gain the benefits of organized data. Elimination of pasteurella pneumotropica from a mouse. A beneficial research tool for use by geneticists and researchers. Transgenic software releases technical white paper for its.
Smart colony management has the it resources to immediately assist with increased workflow productivity and data management. Animal colony management has been an issue of concern for many years 18. The rodentsql application is composed of colony management, experimentprotocol management and report functions. Anybody who works with transgenic mice will encounter the problem of dealing with all the information that is needed to maintain the colony. Soft mouse db v3 allows life scientists conducting research with mouse models to efficiently store and manipulate data associated with transgenic mouse generation, mouse breeding and genetics, mouseline colony maintenance and mouse related experiments. The developer responded very promptly to resolve our questions. Mouse up hypercardbased software for tracking transgenic mice mac rat base. Managing transgenic breeding colonies is challenging even for smaller institutions. Transgenic mice custom transgene expression taconic. Its important to determine the number of breeding pairs you need to supply sufficient mice for your experiments. So, why work on table file when you can work online in the 21th centuary. National institute of environmental health sciences, national institutes of health. It defines guidelines necessary to establish the colony, and describes screening for germline transmission, marking the mice for easy and consistent identification, and genotyping dna by pcr or southern blotting analysis. Softmouse db mouse colony management solution softmouse database softmouse db softmouse db is a transgenic mouse breeding and colony maintenance recordkeeping.
However, there is a wide spectrum of quality and ease of use associated with. Mouse colony database software management internet. Download our mouse colony management software, quick guides, and charts with additional information about our custom animal models. Softmousedb mouse colony transgenic, knockout, mouse, mice. Jun 06, 2018 thus, essential to the efficient management and financial survival of a transgenic colony is the ability to rapidly generate and communicate genotyping data, breeding instructions, and breeding productivity between the end users, the animal care staff, and the genotyping staff. Leave pair together continuously, whenever possible, to maximize production. Auroras guide to mouse colony management at mit aurora burds connor, feb 2007. Monastersky gm, geistfeld jg 2002, transgenic and knockout mice. The management of mouse colonies created by gene targeting is described in this unit. Look at the color dot so you can plan your weekly tasks accordingly. This video tutorial will show you how to add and edit mice in the jax colony management system web application. The softmouse db mouse colony software management recordkeeping system provides core features designed for worldclass researchers who conduct mouse model experiments in a wide range of life science research fields including genetics, embryology, immunology. There are a number of transgenic colony management software packages available commercially. Maintaining a breeding colony of mice is one method of generating and then ensuring an available supply of experimental subjects with desired characteristics.
Nov 25, 2009 iseehear softmousedb mouse colony transgenic management database software 1. Net v4 mouse colony management software has options for tracking mice, cages, weaning, breeding and transgenic and knockout mouse mice colonies. Although mice breed readily when left to themselves, it is helpful to have a working knowledge of. Softmouse db online mouse colony management efficiently allows researchers to create and manipulate records associated with mousebased research, including transgenic mouse generation, mouse breeding and genetics, developmental studies, mouseline colony maintenance, cryopreservation and much more.
It defines guidelines necessary to establish the colony, and describes screening for germline. It is a challenge for us to consistently record data. Mousej is a free mouse colony management software designed for laboratories. Jul 27, 2018 the rodentsql application is composed of colony management, experimentprotocol management and report functions. Specialized for transgenic mouse breeding and mouseline colony maintenance. Transgenic knockout mouse colony software 30 day free trial presentation s. Ideal for animal technicians and biomedical researchers in laboratories, breeding cores, animal facilities. Free softmousedb v3 is a webbased mouse colony management and record tracking database. Softmouse dbs highly configurable, rolebased core engine helps to ensure that the management of mouse breeding and associated experimental data is responsive to the needs of the researcher, technician, lab manager and principal investigator. Free online mouse colony management software for labs on a. Transgenic breeding colony management software from the cloud. But as the colony grows and as you try to associate additional information tissue, samples, litters. Auroras guide to mouse colony management aurora burds connor, 2006 breeding mice in the laboratory is one method of ensuring an available supply of experimental subjects with desired characteristics.
A webbased lab mouse colony laboratory information management software system. Micemanager online management software of laboratory. Breeding core, transgenic core, animal facility and labs our responsibilities are to help breeding cores, transgenic cores, animal facilities and labs gain the benefits of organized data management. Transgenic knockout mouse colony software model organism. Thus, essential to the efficient management and financial survival of a transgenic colony is the ability to rapidly generate and communicate genotyping data, breeding. Online mouse colony management software softmousedb v3 internet colony management softmouse mouse colony management database for breeding and managing transgenic, cre and knockout mouse knockout mice colonies. Iseehear softmousedb mouse colony transgenic management.
However, there is a wide spectrum of quality and ease of use associated with each. Every other entity has a relationship with the mouse id which facilitates complete tracking over other parameters like generations, genotype tracking and mouse caging. Definition a mouse that contains stably inherited dna which has been inserted randomly into the genome. If the colony is small and youre just one person, an excel spreadsheet can work. The core features of the softmouse db mouse colony software management database have been organized to provide these multiple views in the form of various tables and lists. We facilitate the teaching and training of staff members on an as needed basis, as defined by the client, to ensure the optimization of all colony management. See an example and get a mouse colony management calendar template. Softmousedb mouse colony transgenic, knockout, mouse, mice breeding and colony management subscription plan 30 day free trial. Internet colony management softmouse mouse colony management database for breeding and managing transgenic, cre and knockout mouse knockout mice colonies. Apply to research associate, junior specialist, senior technician and more. Although mice breed readily when left to themselves, it is.
Request pdf transgenic mouse colony management this unit describes strategies and methods used to establish a colony of transgenic mice. You can move mice and cages around just like in real life. Basic mating and genotyping strategies are introduced. Mouse colony database software management internet colony. Sep 28, 2017 anybody who works with transgenic mice will encounter the problem of dealing with all the information that is needed to maintain the colony. Ideal for animal technicians and biomedical researchers in laboratories. Microsoft excel spreadsheetbased animal colony management. Similarly, all software requires some level of technical support, which would again be dependent on the responsiveness of the company providing the software. Internet colony management mouse colony software management. Micemanager online management software of laboratory mouse. I am a new principal investigator and my lab is preparing to start up several mouse projects. New features have been released to improve ease of use of key edit pages within the softmousedb transgenic mouse breeding and colony maintenance recordkeeping system posted in uncategorized tagged breeding, colony, database, knock out, mice, mouse, relational, software, transgenic leave a comment. Breeding colony management software from the cloud.
Transgenic animals, and mice in particular, are widely used in research today. Mousej was designed to maintain only the essential information which makes it simple to read and edit. Softmouse db transgenic mouse breeding colony management database software. Breeding strategies for maintaining colonies of laboratory mice. Auroras guide to mouse colony management aurora burds connor, 2006 breeding mice in the laboratory is one method of ensuring an available supply of experimental subjects with desired. The softmouse db mouse colony software management recordkeeping system provides core features designed for worldclass researchers who conduct mouse model experiments in a wide range of life science research fields including genetics, embryology, immunology, neuroscience, genomics, stem cell research and cancer research. Every taconic transgenic model ttm carries a label license granting you a license under taconics inlicensed patent right s to use the model in your research. Software for rodent breeders neuro mouse, software database of murine neurological information for pc. The inserted gene sequence the transgene may or may not be derived from mouse.
Identification of transgenic mice by pcr analysis of saliva. Introducing the k18hace2 transgenic mouse for coronavirus research. The central entity of the rodentsql module is the mouse id. An improved method of genomic dna extraction for screening transgenic mice. Likewise if the mice are born in the beginning of the week, you will need to wean on monday.
It was developed by a mouse researcher to satisfy the need for simplicity, usability, and interactivity. Softmouse tracks mice, rats, breeding, pedigrees, cages, litters, complex genotypes, mouselines, transgenic animals. Th ese techniques have been developed and used by th e jackson laboratory for over 75 years. Can anyone recommend a mouse colony management software. The breeding colony size planning worksheet pdf is a very useful resource. We have more than three transgenic mice colonies in our lab. Ideally, a free or relatively inexpensive system used to track and analyze breeding patterns in a transgenic. Random transgenic mice taconics custom transgenics program employs pronuclear microinjection technology to generate geneticallymodified founder animals.
Transgenic mouse services better solutions to meet your. Ideally, a free or relatively inexpensive system used to track and analyze breeding patterns in a transgenic mouse line. Softmouse db transgenic mouse breeding colony management database. The evolution of modern dna techniques over the last 15 years has revolutionized the development of new transgenic animal models. Im interested in the soft mouse colony management software to manage our breeding and. Soft mouse db v3 allows life scientists conducting research with mouse models to efficiently. Oct 01, 20 this video tutorial will show you how to add and edit mice in the jax colony management system web application. Can anyone recommend a mouse colony management software system. Darmstadt, germany round rock, tx, usa jan 11, 2016. Softmouse database, the leading brand in online mouse colony management software.
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